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What are CEOs across industries doing to build resilience and strong cultures in an age of uncertainty? In this Future of Business series, IdeaCast hosts Alison Beard and Adi Ignatius sat down with four leading CEOs to understand where global business is going. In this episode, host Alison Beard speaks with Noubar Afeyan, the CEO of Flagship Pioneering and Chairman of Moderna. Afeyan shares the organizational models and practices that work best to produce innovation, the difference between managing risk and managing uncertainty, and what separates true breakthrough innovation from everyday, incremental improvements.

It's harder than ever for companies to get their marketing messages in front of the right customers. One increasingly popular -- but also risky -- tactic is fastvertising, the rapid development of ads that tap into a cultural moment, aiming to increase brand relevance and awareness. Harvard Business School associate professor Ayelet Israeli shares pitch-perfect examples, including those from her coauthor, the actor Ryan Reynolds, and his marketing firm Maximum Effort. She explains the importance of timing, describes the talent, culture, and processes you need to succeed, and outlines how to extend the impact of these ads. Ayelet, along with Leonard Schlesinger, Matt Higgins, and Ryan Reynolds, wrote the HBR article "Marketing at the Speed of Culture."

Even in difficult times, leadership must be about empathy, authenticity, fairness and service. That's according to Darren Walker, the outgoing CEO of the Ford Foundation, a nonprofit with an endowment of billions of dollars and a charge to reduce poverty and injustice. Drawing on his own upbringing in rural Texas to his time at the helm of one of the world’s largest philanthropies, Walker explains how inequality erodes hope, why discomfort is essential for meaningful change, and how leaders can build the courage to speak honestly.

Vijay Govindarajan explains how to create a new business while optimizing an already existing one.

The five components of emotional intelligence and how to improve each.

You’re juggling a lot of different priorities. Clarify which one is most important. That way, the next time you feel torn between two commitments, you’ll know which one deserves your attention first.